Nitinol is an alloy of nickel and titanium, which are not significantly toxic to biological tissues. The nickel content is about 55.8% - 56.06%. It is a shape memory alloy and contains a variety of biocompatible metals or metal implants used in combination with other biomaterials. It is generally considered to be standard for many types of implants, so it will not be toxic to our cells.
Its superelastic properties are more similar to bones, so it is widely used in the biomedical field, such as human implant markers, stents, heart valve tools, bone anchors, staplers, septal defect repair devices and implants. Nitinol alloy can be widely used in the medical field, which depends on its biocompatibility, which is an important factor in biomedical applications, which means that the materials we implant into the human body need to be non-toxic, harmless to the human body, and have a low risk of triggering an immune response.
What is the biocompatibility of nickel-titanium alloy?
Biocompatibility refers to the biological response produced by a material after it is implanted into an organism. For organisms, an ideal material should have good biocompatibility, that is, good interaction with biological tissues. The biocompatibility of nitinol is mainly manifested in the following points:
- 1.No toxicity to human cells.
- 2. No reaction in human skin.
- 3. No excessive inflammation or rejection reaction.
- 4. No allergic reaction to the skin.
Niti wire is a commonly used biomaterial, especially in the development of stents and medical guidewire technology. It is also a metal alloy widely used in medical implants, especially catheter components.
As a metal alloy material with unique properties, Nitinol has received widespread attention for its biocompatibility. In medical applications, it can not only effectively support and repair tissues, but also reduce the rejection of foreign bodies by organisms and reduce the incidence of complications. Therefore, Nitnol shape memory alloy has broad application prospects in the medical field and will bring more advantages to human health. If you want to know more about nitinol, please contact amybai2010@zwmet.com or 0086-18161909780 (WhatsApp), our technical team will be there to answer your questions at any time.
Reference:
1. Nitinol alloy wire cytotoxicity test, refer to GB/T 16886.5-2017 MTT, MEM extraction with 10% fetal bovine serum.
2. Nitinol wire intradermal reaction test, refer to GB/T 16886.10-2017, 0.9% sodium chloride injection extraction.
3. NiTi wire skin sensitization test, refer to GB/T 16886.10-2017, guinea pig maximum dose test, 0.9% sodium chloride injection extraction.
4.Biocompatibility of Implants http://www.corrosion-doctors.org/Implants/biocompatib.htm
5. https://en.wikipedia.org/wiki/Nitinol_biocompatibility.
